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- Title
Assessment of Ultrasound / Radio-guided Occult Lesion Localization in Non-palpable Breast Lesions.
- Authors
Alamdaran, Seyed Ali; Farokh, Donia; Haddad, Ayda Sharifi; Daghighi, Navid; Modoodi, Elaheh; Sadeghi, Ramin; Forghani, Mohammad Naser; Fattahi, Asieh Sadat
- Abstract
Objective(s): Controversy exists about the localization of non-palpable breast lesions. In many countries, the gold standard for the diagnosis of these lesions is needle localization due to its accuracy. This study sought to compare the ultrasoundand radio-guided occult lesion localization (ROLL) as a simple method with the conventional procedures in terms of their diagnostic power. Methods: This study was conducted on 94 patients with non-palpable breast lesions detected by ultrasonography and localized by the combination of ultrasonography and using radiopharmaceuticals. One to ten hours prior to surgery, 0.1-0.2 ml (equivalent to 0.5-1 mCi) of Tc-99m-phytate was injected to the lesion under the guidance of ultrasonography. Then, the lesion was localized using a hand-held gamma probe, and excision of the lesion was performed according to its radioactivity signal. Data analysis was performed using SPSS, version 16. Results: Benign and malignant pathologic results were observed in 77 (81.9%) and 17(18.1%) of the patients, respectively, and the mean volume of the excised tissue was 26.29±27 mm3. 79 patients had a solitary lesion (84%), 55 in the left breast (58.5%) and 39 in superolateral quadrant (41.5%). The mean size of the lesions was 15.7 mm in diameter (ranging from 4 to 34 mm). Additionally, there was a need to secondary surgery in 3 (3.2%) patients and inappropriate localization in 6 (6.4%) patients (subcutaneous or intra-ductal spread of radiodrug). Conclusion: Combination of ultrasound- and radio-guided localization methods for localizing non-palpable breast lesions is a simple and acceptable method for localization with no significant complications. For radio-drug spread and subsequent excessive excised tissue volume, subcutaneous and intra-ductal lesions are not suitable indication for ROLL.
- Subjects
RADIOPHARMACEUTICALS; BREAST
- Publication
Asia Oceania Journal of Nuclear Medicine & Biology, 2018, Vol 6, Issue 1, p10
- ISSN
2322-5718
- Publication type
Article
- DOI
10.22038/aojnmb.2017.9898