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- Title
Antibodies to human leucocyte antigens indicate subpopulations of microglia in human retina.
- Authors
Penfold, P.L.; Madigan, M.C.; Provis, J.M.
- Abstract
Monoclonal antibodies to human leucocyte antigens, including anti-CD45 and anti-CD68, have been used to describe microglia in flatmounts of normal adult human retina for the first time. Anti-CD45 (the leucocyte common antigen) intensely labeled large numbers of cells in a regular distribution across the retina; anti-CD68 and anti-macrophage antibodies labeled fewer cells with distinctive morphologies, suggesting the presence of subpopulations of microglia in the human retina expressing leucocyte antigens.
- Publication
Visual Neuroscience, 1991, Vol 7, Issue 4, p383
- ISSN
0952-5238
- Publication type
Article
- DOI
10.1017/S0952523800004879