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- Title
Efficacy of (+)-Lariciresinol to Control Bacterial Growth of Staphylococcus aureus and Escherichia coli O157:H7.
- Authors
Bajpai, Vivek K.; Shukla, Shruti; Paek, Woon K.; Jeongheui Lim; Kumar, Pradeep; Kumar, Pankaj; MinKyun Na
- Abstract
This study was undertaken to assess the antibacterial potential of a polyphenolic compound (+)-lariciresinol isolated from Rubia philippinensis against selected foodborne pathogens Staphylococcus aureus KCTC1621 and Escherichia coli O157:H7. (+)-Lariciresinol at the tested concentrations (250 µg/disk) evoked a significant antibacterial effect as a diameter of inhibition zones (12.1-14.9 mm) with minimum inhibitory concentration (MIC). and minimum bactericidal concentration values of 125-250 and 125-250 µg/mL, respectively. Furthermore, (+)-lariciresinol at MIC showed reduction in bacterial cell viabilities, efflux of potassium (K+) ions and release of 260 nm materials against E. coli O157:H7 and S. aureus KCTC1621. Moreover, deteriorated cell wall morphology of E. coli O157:H7 and S. aureus KCTC1621 cells treated with (+)-lariciresinol at MIC further confirmed its inhibitory effect against the tested pathogens, suggesting it to be an alternative means of antimicrobials.
- Subjects
PHENYLPROPANOIDS; BACTERIAL growth prevention; ANTI-infective agents; STAPHYLOCOCCUS aureus; ESCHERICHIA coli; FOOD pathogens; THERAPEUTICS
- Publication
Frontiers in Microbiology, 2017, Vol 8, p1
- ISSN
1664-302X
- Publication type
Article
- DOI
10.3389/fmicb.2017.00804