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- Title
Net contribution and predictive ability of the CUN-BAE body fatness index in relation to cardiometabolic conditions.
- Authors
Davila-Batista, Veronica; Molina, Antonio J.; Vilorio-Marqués, Laura; Lujan-Barroso, Leila; de Souza-Teixeira, Fernanda; Olmedo-Requena, Rocío; Arias de la Torre, Jorge; García-Martínez, Lidia; Álvarez-Álvarez, Laura; Freisling, Heinz; Llorca, Javier; Delgado-Rodríguez, Miguel; Martin, Vicente
- Abstract
Background: The CUN-BAE (Clínica Universidad de Navarra-Body adiposity estimator) index is an anthropometric index based on age, sex and body mass index (BMI) for a refined prediction of body fatness in adults. CUN-BAE may help detect metabolically unhealthy individuals with otherwise normal weight according to BMI or waist circumference (WC). The aim of this study was to evaluate whether CUN-BAE, independent of its components (BMI, age and sex), was associated with cardiometabolic conditions including arterial hypertension, diabetes mellitus and metabolic syndrome (MetS). Methods: The ENRICA study was based on a cross-sectional sample of non-institutionalized men and women representative of the adult Spanish population. Body weight, height, and WC were measured in all participants. The residual of CUN-BAE (rCUN-BAE), i.e. the part of the index not explained by its components, was calculated. The associations of CUN-BAE, rCUN-BAE, BMI and WC with hypertension, diabetes and MetS were analysed by multivariate logistic regression, and the Akaike information criterion (AIC) was calculated. Results: The sample included 12,122 individuals. rCUN-BAE was associated with hypertension (OR 1.14, 95% CI 1.07–1.21) and MetS (OR 1.48, 1.37–1.60), but not with diabetes (OR 1.05, 0.94–1.16). In subjects with a BMI < 25 kg/m2, CUN-BAE was significantly associated with all three outcome variables. CUN-BAE was more strongly associated with the cardiometabolic conditions than BMI and WC and fit similar AICs. Conclusions: The CUN-BAE index for body fatness was positively associated with hypertension, diabetes and MetS in adults independent of BMI or WC. CUN-BAE may help to identify individuals with cardiometabolic conditions beyond BMI, but this needs to be confirmed in prospective settings.
- Subjects
DIABETES risk factors; PULMONARY hypertension; METABOLIC syndrome risk factors; METABOLIC disorders; OBESITY complications; ADIPOSE tissues; AGE distribution; ANTHROPOMETRY; CARDIOVASCULAR diseases risk factors; LONGITUDINAL method; MULTIVARIATE analysis; OBESITY; RISK assessment; SEX distribution; MULTIPLE regression analysis; BODY mass index; CROSS-sectional method; WAIST circumference; DISEASE risk factors; HYPERTENSION risk factors
- Publication
European Journal of Nutrition, 2019, Vol 58, Issue 5, p1853
- ISSN
1436-6207
- Publication type
Article
- DOI
10.1007/s00394-018-1743-9