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- Title
Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Caused by Itraconazole in a 17-Year-Old Girl.
- Authors
Pires Pereira, Helena; Coutinho, Iolanda Alen; Carrapatoso, Isabel; Todo-Bom, Ana
- Abstract
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe adverse drug-induced hypersensitivity reaction. We report a case of DRESS syndrome in a 17-year-old female caused by itraconazole, confirmed by patch testing, that required treatment with both corticotherapy and cyclosporine. Our case highlights the importance of clinical suspicion of this syndrome in pediatric age and the novelty of an antifungal drug being identified as the culprit.
- Subjects
PHYSICAL diagnosis; ADRENOCORTICAL hormones; SKIN tests; FEVER; INTRAVENOUS therapy; NONOPIOID analgesics; DRESS syndrome; EXANTHEMA; CREATINE kinase; CYCLOSPORINE; MUSCLE weakness; EOSINOPHILIA; ITRACONAZOLE; VULVOVAGINAL candidiasis; MYOSITIS; PREDNISONE; ALANINE aminotransferase; ASPARTATE aminotransferase
- Publication
Pediatric Allergy, Immunology & Pulmonology, 2023, Vol 36, Issue 4, p143
- ISSN
2151-321X
- Publication type
Article
- DOI
10.1089/ped.2023.0066