We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Diagnostic Value of Irisin and Visfatin in Experimental Testicular Torsion.
- Authors
Saraç, Fatma; Yeniocak, Selman; Sarsu, Sevgi Büyükbeşe; Yücetaş, Esma; Olgaç, Vakur; Toptaş, Mehmet; Koldaş, Macit
- Abstract
Aim: Testicular torsion (TT) is one of the most important causes of acute scrotum in children and young men. Very scarce number of serum laboratory parameters might be used in the early diagnosis of patients with TT. We planned this study in consideration of the possible significance of the changes in serum irisin and visfatin levels in the diagnosis of TT. Methods: We used 28 rats in four groups. In the control group, blood samples and specimens of testicular tissue were collected at 2nd and 4th hours after torsion. In the torsion groups, the left testis was twisted, and blood samples and specimens of the testicular tissue were collected at the 2nd and 4th hours for analysis. Results: There was no statistically significant difference in mean irisin and visfatin levels at the 2nd and 4th hours between rats with TT and controls. There was no statistically difference between mean irisin and vistatin levels at the 2nd hour and at the 4th hour in torsion and control groups. Conclusion: In our experimental TT method, we could not find a statistically significant difference between serum levels of irisin and visfatin. We assume that further studies are needed on this issue.
- Subjects
SPERMATIC cord torsion; ANIMAL experimentation; BLOOD testing; EXPERIMENTAL design; TRANSFERASES; TORSION abnormality (Anatomy); DIAGNOSIS
- Publication
Medical Bulletin of Haseki / Haseki Tip Bulteni, 2017, Vol 55, Issue 4, p274
- ISSN
1302-0072
- Publication type
Article
- DOI
10.4274/haseki.65375