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- Title
A fast cardiac electromechanics model coupling the Eikonal and the nonlinear mechanics equations.
- Authors
Stella, Simone; Regazzoni, Francesco; Vergara, Christian; Dedé, Luca; Quarteroni, Alfio
- Abstract
We present a new model of human cardiac electromechanics for the left ventricle where electrophysiology is described by a Reaction–Eikonal model and which enables an off-line resolution of the reaction model, thus entailing a big saving of computational time. Subcellular dynamics is coupled with a model of tissue mechanics, which is in turn coupled with a Windkessel model for blood circulation. Our numerical results show that the proposed model is able to provide a physiological response to changes in certain variables (end-diastolic volume, total peripheral resistance, contractility). We also show that our model is able to reproduce with high accuracy and with a considerably lower computational time the results that we would obtain if the monodomain model should be used in place of the Eikonal model.
- Subjects
NONLINEAR mechanics; NONLINEAR equations; TISSUE mechanics; CONTRACTILITY (Biology); BLOOD circulation; CIRCULATION models; ELECTROPHYSIOLOGY
- Publication
Mathematical Models & Methods in Applied Sciences, 2022, Vol 32, Issue 8, p1531
- ISSN
0218-2025
- Publication type
Article
- DOI
10.1142/S021820252250035X