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- Title
Host specificity of <italic>Enterocytozoon bieneusi</italic> genotypes in Bactrian camels (<italic>Camelus bactrianus</italic>) in China.
- Authors
Qi, Meng; Li, Junqiang; Zhao, Aiyun; Cui, Zhaohui; Wei, Zilin; Jing, Bo; Zhang, Longxian
- Abstract
Background: <italic>Enterocytozoon bieneusi</italic> is an obligate, intracellular fungus and is commonly reported in humans and animals. To date, there have been no reports of <italic>E. bieneusi</italic> infections in Bactrian camels (<italic>Camelus bactrianus</italic>). The present study was conducted to understand the occurrence and molecular characteristics of <italic>E. bieneusi</italic> in Bactrian camels in China. Results: Of 407 individual Bactrian camel fecal specimens, 30.0% (122) were <italic>E. bieneusi</italic>-positive by nested polymerase chain reaction (PCR) based on internal transcriber spacer (ITS) sequence analysis. A total of 14 distinct <italic>E. bieneusi</italic> ITS genotypes were obtained: eight known genotypes (genotype EbpC, EbpA, Henan-IV, BEB6, CM8, CHG16, O and WL17), and six novel genotypes (named CAM1 to CAM6). Genotype CAM1 (59.0%, 72/122) was the most predominant genotype in Bactrian camels in Xinjiang, and genotype EbpC (18.9%, 23/122) was the second-most predominant genotype. Phylogenetic analysis revealed that six known genotypes (EbpC, EbpA, WL17, Henan-IV, CM8 and O) and three novel genotypes (CAM3, CAM5 and CAM6) fell into the human-pathogenic group 1. Two known genotypes (CHG16 and BEB6) fell into the cattle host-specific group 2. The novel genotypes CAM1, CAM 2 and CAM4 cluster into group 8. Conclusions: To our knowledge, this is the first report of <italic>E. bieneusi</italic> in Bactrian camels. The host-specific genotype CAM1 was the predominant genotype, which plays a negligible role in the zoonotic transmission of <italic>E. bieneusi</italic>. However, the second-most predominant genotype, EbpC, has greater zoonotic potential.
- Subjects
FUNGI; HOST specificity (Biology); BACTRIAN camel; ZOONOSES; POLYMERASE chain reaction; INFECTIOUS disease transmission
- Publication
Parasites & Vectors, 2018, Vol 11, p1
- ISSN
1756-3305
- Publication type
Article
- DOI
10.1186/s13071-018-2793-9