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- Title
Long-Term Results of Partial Splenic Artery Embolization as Supplemental Treatment for Portal-Systemic Encephalopathy.
- Authors
Yoshida, Hiroshi; Mamada, Yasuhiro; Taniai, Nobuhiko; Yamamoto, Kazuhito; Kaneko, Masahiro; Kawano, Youichi; Mizuguchi, Yoshiaki; Kumazaki, Tatsuo; Tajiri, Takashi
- Abstract
OBJECTIVES: To present long-term results of angiographic partial splenic artery embolization (PSE) as a supplemental treatment of portal-systemic encephalopathy.METHODS: Twenty-five patients with portal-systemic encephalopathy were divided into two groups: 14 patients underwent transportal obliteration and/or balloon-occluded retrograde transvenous obliteration (BRTO) of portal-systemic shunts (PSS), followed by PSE (PSE(+) group), and 11 patients underwent only transportal obliteration and/or BRTO of PSS (PSE(−) group).RESULTS: Portal venous pressures pretreatment was similar to posttreatment in the PSE(+) group, but lower than posttreatment in the PSE(−) group. Serum ammonia levels were higher at pretreatment than at 1 wk posttreatment in both groups, but the levels in the two groups were similar at pretreatment, 1 wk, 3 months, 3 yr, 4 yr, and 5 yr posttreatment. However, serum ammonia levels were lower in the PSE(+) group than in the PSE(−) group 6 months, 9 months, 1 yr, and 2 yr posttreatment. Grades of encephalopathy were higher at pretreatment than at 1 wk posttreatment in both groups, but the levels in the two groups were similar at pretreatment, 1 wk, 2 yr, 3 yr, 4 yr, and 5 yr posttreatment. However, grades of encephalopathy were lower in the PSE(+) group than in the PSE(−) group 3 months, 6 months, 9 months, and 1 yr posttreatment.CONCLUSIONS: Obliteration of PSS followed by PSE benefit patients with portal-systemic encephalopathy.(Am J Gastroenterol 2005;100:43–47)
- Subjects
ANGIOGRAPHY; BLOOD vessels; BLOOD plasma; NITROGEN compounds; VENOUS pressure; BLOOD pressure; AMMONIA
- Publication
American Journal of Gastroenterology (Springer Nature), 2005, Vol 100, Issue 1, p43
- ISSN
0002-9270
- Publication type
Article
- DOI
10.1111/j.1572-0241.2005.40559.x