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- Title
Site‐Selective C−H Bond Functionalization of Chromones and Coumarins.
- Authors
Kang, Dahye; Ahn, Kukcheol; Hong, Sungwoo
- Abstract
Abstract: Chromones and coumarins are privileged scaffolds that are widely distributed in natural products, synthetic building blocks, pharmaceutical agents, and functional materials. Chromones and coumarins have chemically distinct C−H bonds that can be converted into valuable functional groups for the purpose of constructing compounds with diverse pharmacological profiles. Recent advances in the development of methods and an understanding of the innate electronic properties of chromones and coumarins have led to approaches that provide high levels of site‐selectivity. This focus review highlights recent innovative strategies for the efficient modification of these structural frameworks through site‐selective C−H bond functionalizations.
- Subjects
CHROMONES; COUMARINS; SYNTHETIC building materials
- Publication
Asian Journal of Organic Chemistry, 2018, Vol 7, Issue 7, p1136
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.201800128