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CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6205, doi. 10.1002/alz.14103
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Schindler, Suzanne E.;
- Kate, Mara ten;
- Reus, Lianne M.;
- Dobricic, Valerija;
- Tijms, Betty M.;
- Benzinger, Tammie L. S.;
- Cruchaga, Carlos;
- Teunissen, Charlotte E.;
- Ramakers, Inez;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Vandenberghe, Rik;
- Schaeverbeke, Jolien;
- Engelborghs, Sebastiaan;
- Roeck, Ellen De;
- Popp, Julius;
- Peyratout, Gwendoline;
- Tsolaki, Magda
Publication type:
Article
Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 10, p. 3522, doi. 10.1093/brain/awae090
By:
- Reus, Lianne M;
- Jansen, Iris E;
- Tijms, Betty M;
- Visser, Pieter Jelle;
- Tesi, Niccoló;
- Lee, Sven J van der;
- Vermunt, Lisa;
- Peeters, Carel F W;
- Groot, Lisa A De;
- Hok-A-Hin, Yanaika S;
- Chen-Plotkin, Alice;
- Irwin, David J;
- Hu, William T;
- Meeter, Lieke H;
- Swieten, John C van;
- Holstege, Henne;
- Hulsman, Marc;
- Lemstra, Afina W;
- Pijnenburg, Yolande A L;
- Flier, Wiesje M van der
Publication type:
Article
Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01577-3
By:
- Reus, Lianne M.;
- Jansen, Iris E.;
- Mol, Merel O.;
- van Ruissen, Fred;
- van Rooij, Jeroen;
- van Schoor, Natasja M.;
- Tesi, Niccolò;
- Reinders, Marcel J. T.;
- Huisman, Martijn A.;
- Holstege, Henne;
- Visser, Pieter Jelle;
- de Boer, Sterre C. M.;
- Hulsman, Marc;
- Ahmad, Shahzad;
- Amin, Najaf;
- Uitterlinden, Andre G.;
- Ikram, Arfan;
- van Duijn, Cornelia M.;
- Seelaar, Harro;
- Ramakers, Inez H. G. B.
Publication type:
Article
Post‐GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 5044, doi. 10.1002/alz.13848
By:
- Panyard, Daniel J.;
- Reus, Lianne M.;
- Ali, Muhammad;
- Liu, Jihua;
- Deming, Yuetiva K.;
- Lu, Qiongshi;
- Kollmorgen, Gwendlyn;
- Carboni, Margherita;
- Wild, Norbert;
- Visser, Pieter J.;
- Bertram, Lars;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Gobom, Johan;
- Western, Dan;
- Sung, Yun Ju;
- Carlsson, Cynthia M.;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Cruchaga, Carlos
Publication type:
Article
Dissecting the shared genetic basis of Alzheimer's disease and hippocampal volumes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082963
By:
- Jiang, Chenyang;
- van der Lee, Sven J;
- van der Flier, Wiesje M.;
- Tijms, Betty M.;
- Reus, Lianne M.
Publication type:
Article
Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score.
Published in:
BMC Neurology, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12883-022-02925-6
By:
- Tomassen, Jori;
- den Braber, Anouk;
- van der Lee, Sven J.;
- Reus, Lianne M.;
- Konijnenberg, Elles;
- Carter, Stephen F.;
- Yaqub, Maqsood;
- van Berckel, Bart N.M.;
- Collij, Lyduine E.;
- Boomsma, Dorret I.;
- de Geus, Eco J.C.;
- Scheltens, Philip;
- Herholz, Karl;
- Tijms, Betty M.;
- Visser, Pieter Jelle
Publication type:
Article
Cross-disorder and disorder-specific deficits in social functioning among schizophrenia and alzheimer's disease patients.
Published in:
PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0263769
By:
- Saris, Ilja M. J.;
- Aghajani, Moji;
- Jongs, Niels;
- Reus, Lianne M.;
- van der Wee, Nic J. A.;
- Bilderbeck, Amy C.;
- Winter van Rossum, Inge;
- Arango, Celso;
- de la Torre-Luque, Alejandro;
- Malik, Asad;
- Raslescu, Andreea;
- Dawson, Gerard R.;
- Ayuso-Mateos, José L.;
- Kas, Martien J.;
- Penninx, Brenda W. J. H.
Publication type:
Article
Associations between vascular risk factors and brain MRI indices in UK Biobank.
Published in:
European Heart Journal, 2019, v. 40, n. 28, p. 2290, doi. 10.1093/eurheartj/ehz100
By:
- Cox, Simon R;
- Lyall, Donald M;
- Ritchie, Stuart J;
- Bastin, Mark E;
- Harris, Mathew A;
- Buchanan, Colin R;
- Fawns-Ritchie, Chloe;
- Barbu, Miruna C;
- Nooij, Laura de;
- Reus, Lianne M;
- Alloza, Clara;
- Shen, Xueyi;
- Neilson, Emma;
- Alderson, Helen L;
- Hunter, Stuart;
- Liewald, David C;
- Whalley, Heather C;
- McIntosh, Andrew M;
- Lawrie, Stephen M;
- Pell, Jill P
Publication type:
Article
Automated FreeSurfer segmentation and visual quality control in 10,000 MRI scans from a large memory clinic cohort.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078805
By:
- Bocancea, Diana I.;
- den Braber, Anouk;
- Jiang, Chenyang;
- Coomans, Emma M.;
- van Unnik, Annemartijn A. J. M.;
- van Veen, Julia M.L.;
- Ribberink, Marieke;
- Reijner, Niels;
- Saddal, Shalina;
- Mastenbroek, Sophie E;
- van Gils, Aniek M.;
- Kluin, Caro M.;
- de Leeuw, Diederick Martijn;
- Vromen, Eleonora M.;
- Bekkers, Lotta;
- Georgallidou, Margarita;
- van der Landen, Sophie M.;
- Baumann, Jana M.;
- Heuvelink, Joost;
- Reus, Lianne M.
Publication type:
Article
Cerebrospinal fluid metabolome‐wide association study of Alzheimer's disease provides insight into molecular pathways.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078688
By:
- Reus, Lianne M.;
- Boltz, Toni;
- Francia, Marcelo;
- Bot, Merel;
- Loohuis, Loes Olde;
- Teunissen, Charlotte E.;
- Ophoff, Roel;
- Tijms, Betty;
- van der Lee, Sven J;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Ramesh, Naren
Publication type:
Article
Automated FreeSurfer segmentation and visual quality control in 10,000 MRI scans from a large memory clinic cohort.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081841
By:
- Bocancea, Diana I.;
- den Braber, Anouk;
- Jiang, Chenyang;
- Coomans, Emma M.;
- van Unnik, Annemartijn A. J. M.;
- van Veen, Julia M.L.;
- Ribberink, Marieke;
- Reijner, Niels;
- Saddal, Shalina;
- Mastenbroek, Sophie E;
- van Gils, Aniek M.;
- Kluin, Caro M.;
- de Leeuw, Diederick Martijn;
- Vromen, Eleonora M.;
- Bekkers, Lotta;
- Georgallidou, Margarita;
- van der Landen, Sophie M.;
- Baumann, Jana M.;
- Heuvelink, Joost;
- Reus, Lianne M.
Publication type:
Article
Cerebrospinal fluid metabolome‐wide association study of Alzheimer's disease provides insight into molecular pathways.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078688
By:
- Reus, Lianne M.;
- Boltz, Toni;
- Francia, Marcelo;
- Bot, Merel;
- Loohuis, Loes Olde;
- Teunissen, Charlotte E.;
- Ophoff, Roel;
- Tijms, Betty;
- van der Lee, Sven J;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Ramesh, Naren
Publication type:
Article
Evaluating the association between genetically proxied ACE inhibition and dementias.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 9, p. 3894, doi. 10.1002/alz.13062
By:
- Nassan, Malik;
- Daghlas, Iyas;
- Piras, Ignazio S.;
- Rogalski, Emily;
- Reus, Lianne M;
- Pijnenburg, Yolande;
- Cuddy, Leah K.;
- Saxena, Richa;
- Mesulam, M‐Marsel;
- Huentelman, Matt
Publication type:
Article
Identifying Protein Quantitative Trait Loci in the Cerebrospinal Fluid Proteome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059964
By:
- Reus, Lianne M.;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bertram, Lars;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non‐Alzheimer's disease pathophysiology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 3, p. 807, doi. 10.1002/alz.12713
By:
- Delvenne, Aurore;
- Gobom, Johan;
- Tijms, Betty;
- Bos, Isabelle;
- Reus, Lianne M.;
- Dobricic, Valerija;
- Kate, Mara ten;
- Verhey, Frans;
- Ramakers, Inez;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- Vandenberghe, Rik;
- Schaeverbeke, Jolien;
- Gabel, Silvy;
- Popp, Julius;
- Peyratout, Gwendoline;
- Martinez‐Lage, Pablo;
- Tainta, Mikel;
- Tsolaki, Magda;
- Freund‐Levi, Yvonne
Publication type:
Article
Shorter disease duration in females with sporadic frontotemporal dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067557
By:
- de Boer, Sterre C.M.;
- Riedl, Lina;
- Van der lee, Sven J;
- Otto, Markus;
- Anderl‐Straub, Sarah;
- Landin‐Romero, Ramon;
- Sorrentino, Federica;
- Fieldhouse, Jay L.P.;
- Reus, Lianne M.;
- Halliday, Glenda M;
- Galimberti, Daniela;
- Diehl‐Schmid, Janine;
- Ducharme, Simon;
- Piguet, Olivier;
- Pijnenburg, Yolande A.L.
Publication type:
Article
GMNC risk alleles in individuals with Alzheimer's disease are associated with cerebrospinal fluid concentrations of proteins involved in neuronal plasticity and blood brain barrier function.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.065570
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Teunissen, Charlotte E.;
- Bertram, Lars;
- Zetterberg, Henrik;
- Tijms, Betty M.
Publication type:
Article
Social behavior assessment in cognitively impaired older adults using a passive and remote smartphone application.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051698
By:
- Muurling, Marijn;
- Reus, Lianne M.;
- de Boer, Casper;
- Jagesar, Raj;
- Vorstman, Jacob A;
- Kas, Martien JH;
- Visser, Pieter Jelle
Publication type:
Article
Differences in sex distribution between genetic and sporadic FTD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052836
By:
- de Boer, Sterre C.M.;
- Van Der Lee, Sven J;
- Diehl‐Schmid, Janine;
- Riedl, Lina;
- Piguet, Olivier;
- Halliday, Glenda M;
- Galimberti, Daniela;
- Sorrentino, Federica;
- Ducharme, Simon;
- Fieldhouse, Jay L.P.;
- Reus, Lianne M.;
- Pijnenburg, Yolande A.L.
Publication type:
Article
Alzheimer's disease genetic risk variants show brain cell type‐specific associations with protein levels in cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049531
By:
- Reus, Lianne M.;
- Van Der Lee, Sven J;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bertram, Lars;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
Functional interpretation of genetic risk loci for dementia using a protein quantitative trait loci (pQTLs) approach in cerebrospinal fluid: Genetics: Molecular genetics of AD and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040774
By:
- Reus, Lianne M.;
- Jansen, Iris E.;
- Tijms, Betty M.;
- Visser, Pieter Jelle;
- Lemstra, Afina W.;
- Pijnenburg, Yolande A.L.;
- van Der Flier, Wiesje;
- Teunissen, Charlotte E.;
- Campo, Marta Del
Publication type:
Article
O5‐02‐02: DIFFERENTIAL EXPRESSION OF POLYGENIC RISK IN CEREBROSPINAL FLUID PROTEOMIC MEASURES IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1616, doi. 10.1016/j.jalz.2019.06.4841
By:
- Reus, Lianne M.;
- Stringer, Sven;
- Posthuma, Danielle;
- Teunissen, Charlotte E.;
- Scheltens, Philip;
- Pijnenburg, Yolande A.L.;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
P4‐525: ASSOCIATION OF CSF TAU WITH HYPERPLASTICITY IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1515, doi. 10.1016/j.jalz.2019.08.072
By:
- Visser, Pieter Jelle;
- Gobom, Johan;
- Reus, Lianne M.;
- Jansen, Iris E.;
- Tsolaki, Magda;
- Verhey, Frans R.J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, Jose Luis;
- Engelborghs, Sebastiaan;
- Lovestone, Simon;
- Streffer, Johannes;
- Vos, Stephanie J.B.;
- Bos, Isabelle;
- Bertram, Lars;
- Posthuma, Danielle;
- Smit, August B.;
- Blennow, Kaj
Publication type:
Article
Assessment of Social Behavior Using a Passive Monitoring App in Cognitively Normal and Cognitively Impaired Older Adults: Observational Study.
Published in:
JMIR Aging, 2022, v. 5, n. 2, p. 1, doi. 10.2196/33856
By:
- Muurling, Marijn;
- Reus, Lianne M.;
- de Boer, Casper;
- Wessels, Sterre C.;
- Jagesar, Raj R.;
- Vorstman, Jacob A. S.;
- Kas, Martien J. H.;
- Visser, Pieter Jelle
Publication type:
Article
Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Published in:
2022
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Jansen, Iris;
- Dicks, Ellen;
- van der Lee, Sven J.;
- Tsolaki, Magda;
- Verhey, Frans R. J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, José Luís;
- Engelborghs, Sebastiaan;
- Freund-Levi, Yvonne;
- Froelich, Lutz;
- Sleegers, Kristel;
- Dobricic, Valerija;
- Lovestone, Simon;
- Streffer, Johannes
Publication type:
Correction Notice
Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Published in:
2022
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Jansen, Iris;
- Dicks, Ellen;
- van der Lee, Sven J.;
- Tsolaki, Magda;
- Verhey, Frans R. J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, José Luís;
- Engelborghs, Sebastiaan;
- Freund-Levi, Yvonne;
- Froelich, Lutz;
- Sleegers, Kristel;
- Dobricic, Valerija;
- Lovestone, Simon;
- Streffer, Johannes
Publication type:
Correction Notice
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Published in:
Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00521-3
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Jansen, Iris;
- Dicks, Ellen;
- van der Lee, Sven J.;
- Tsolaki, Magda;
- Verhey, Frans R. J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, José Luís;
- Engelborghs, Sebastiaan;
- Freund-Levi, Yvonne;
- Froelich, Lutz;
- Sleegers, Kristel;
- Dobricic, Valerija;
- Lovestone, Simon;
- Streffer, Johannes
Publication type:
Article
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Published in:
Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00521-3
By:
- Visser, Pieter Jelle;
- Reus, Lianne M.;
- Gobom, Johan;
- Jansen, Iris;
- Dicks, Ellen;
- van der Lee, Sven J.;
- Tsolaki, Magda;
- Verhey, Frans R. J.;
- Popp, Julius;
- Martinez-Lage, Pablo;
- Vandenberghe, Rik;
- Lleó, Alberto;
- Molinuevo, José Luís;
- Engelborghs, Sebastiaan;
- Freund-Levi, Yvonne;
- Froelich, Lutz;
- Sleegers, Kristel;
- Dobricic, Valerija;
- Lovestone, Simon;
- Streffer, Johannes
Publication type:
Article
Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants.
Published in:
Cerebral Cortex, 2018, v. 28, n. 8, p. 2959, doi. 10.1093/cercor/bhy109
By:
- Ritchie, Stuart J;
- Cox, Simon R;
- Shen, Xueyi;
- Lombardo, Michael V;
- Reus, Lianne M;
- Alloza, Clara;
- Harris, Mathew A;
- Alderson, Helen L;
- Hunter, Stuart;
- Neilson, Emma
Publication type:
Article

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