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Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0678-6
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- Article
Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
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- Marine Drugs, 2017, v. 15, n. 10, p. 316, doi. 10.3390/md15100316
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- Article
One-pot synthesis of new 3-substituted coumarins by tandem reactions.
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- Journal of Heterocyclic Chemistry, 2007, v. 44, n. 1, p. 193, doi. 10.1002/jhet.5570440130
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- Article
Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1Hchromeno[ 2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities.
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- ARKIVOC: Online Journal of Organic Chemistry, 2017, v. 2017, p. 291, doi. 10.3998/ark.5550190.p010.040
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- Article
Stereoselective synthesis of (2E) 3-amino-2-(1 H-benzimidazol-2-yl)acrylate and symmetric bisacrylates by transamination reactions.
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- Heteroatom Chemistry, 1999, v. 10, n. 6, p. 446, doi. 10.1002/(SICI)1098-1071(1999)10:6<446::AID-HC2>3.0.CO;2-E
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- Article
Regioselective aza-annulation to a heterocyclic ketene aminal: A new route to ethyl 1-oxo-2,3-dihydropyrido-[1,2-a]-(5 H)-perimidine-4-carboxylates.
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- Heteroatom Chemistry, 1998, v. 9, n. 5, p. 523, doi. 10.1002/(SICI)1098-1071(1998)9:5<523::AID-HC10>3.0.CO;2-T
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- Publication type:
- Article
Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases.
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- Molecules, 2015, v. 20, n. 7, p. 12412, doi. 10.3390/molecules200712412
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- Article
Microwave-Assisted Condensation Reactions of Acetophenone Derivatives and Activated Methylene Compounds with Aldehydes Catalyzed by Boric Acid under Solvent-Free Conditions.
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- Molecules, 2015, v. 20, n. 6, p. 11617, doi. 10.3390/molecules200611617
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- Publication type:
- Article
SYNTHESIS AND APPLICATION OF IONIC LIQUID PHASE-SUPPORTED β-AMINOCROTONATE FOR ACCESS TO ASYMMETRIC 1,4- DIHYDROPYRIDINES.
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- Heterocyclic Communications, 2009, v. 15, n. 2, p. 91
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- Publication type:
- Article
Investigation on the synthesis of new 3-[4-(arylalkoxy)phenylethyl]-2-thioxo-1,3-thiazolidin-4-ones and their biological evaluation against cancer cells.
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- Chemistry of Heterocyclic Compounds, 2017, v. 53, n. 3, p. 341, doi. 10.1007/s10593-017-2056-2
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- Article
Acid-induced dimerization of imidates derived from glycine: Synthesis of methyl N-(1,2,5-trisubstituted-4-imidazoyl)glycinates.
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- Heteroatom Chemistry, 1996, v. 7, n. 3, p. 187, doi. 10.1002/(SICI)1098-1071(199605)7:3<187::AID-HC5>3.0.CO;2-7
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- Publication type:
- Article
A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives.
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- Molecules, 2011, v. 16, n. 9, p. 7377, doi. 10.3390/molecules16097377
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- Article
Leucettines, a family of pharmacological inhibitors of DYRKs and CLKs derived from the marine sponge: Natural product Leucettamine B
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- 2012
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- Abstract
Efficiency and selectivity of ionic liquids in microwave‐assisted extraction of major lichen phenolic compounds: a scalable process with recycling of ionic liquids.
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- Phytochemical Analysis, 2021, v. 32, n. 4, p. 592, doi. 10.1002/pca.3008
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- Article
Synthesis of New N,N'-Bis(5-arylidene-4-oxo- 4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation.
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- Scientia Pharmaceutica, 2012, v. 80, n. 4, p. 825, doi. 10.3797/scipharm.1206-04
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- Article
A Convenient Four-Step Synthesis of 1-{β-[3-(4-Methoxy-phenyl)Propoxy]-4-Methoxyphenethyl}-1H-Imidazole Hydrochloride as a Probing Tool for SOCE Assays.
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- Molbank, 2016, v. 2016, n. 4, p. m909, doi. 10.3390/M909
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- Article
A practical multi-step synthesis of ethyl N-functionalized β-amino benzimidazole acrylate derivatives as promising cytotoxic agents.
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- Molecular Diversity, 2018, v. 22, n. 3, p. 685, doi. 10.1007/s11030-018-9824-5
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- Article
New 5-ylidene rhodanine derivatives based on the dispacamide A model.
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- Molecular Diversity, 2014, v. 18, n. 2, p. 375, doi. 10.1007/s11030-014-9509-7
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- Publication type:
- Article
Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 856, doi. 10.3390/ijms19030856
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- Article
Design and Synthesis of Novel N -Benzylidene Derivatives of 3-Amino-4-imino-3,5-dihydro-4 H -chromeno[2,3- d ]pyrimidine under Microwave, In Silico ADME Predictions, In Vitro Antitumoral Activities and In Vivo Toxicity.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 458, doi. 10.3390/ph17040458
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- Article
Design and Microwave Synthesis of New (5 Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5 Z) 2-Amino-5-arylidene-1,3-thiazol-4(5 H)-one as New Inhibitors of Protein Kinase DYRK1A.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1086, doi. 10.3390/ph14111086
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- Publication type:
- Article