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- Title
Outcome of live and deceased donor renal transplantation in patients aged ≥55 years: A single.center experience.
- Authors
Kute, V. B.; Vanikar, A. V.; Shah, P. R.; Gumber, M. R.; Patel, H. V.; Modi, P. R.; Rizvi, S. J.; Shah, V. R.; Modi, M. P.; Kanodia, K. V.; Trivedi, H. L.
- Abstract
Renal transplantation (RTx) has now become an accepted therapeutic modality of choice for elderly ESRD patients. This single-center study was undertaken to evaluate the outcome of RTx in ESRD patients. ≥5 years. A total of 103 patients underwent RTx 79 living related living donors [LD], 24 deceased donors [DD]) at our center. Post-transplant immunosuppression consisted of calcineurin inhibitor-based regimen. The mean donor age was 58.3 years in the LD group and 59.5 years in the DD group. Male recipients constituted 92% in LD and 75% in DD group. In living donor renal transplantation, 1- and 5-year patient survival was 93% and 83.3% respectively and death-censored graft survival was 97.3% and 92.5% respectively. There were 12.6% biopsy proven acute rejection (BPAR) episodes and 12.6% patients were lost, mainly due to infections. In deceased donor renal transplantation, 1- and 5-year patient survival was 79.1% and 74.5% respectively and death-censored graft survival was 95.8% and 85.1% respectively. There were 12.5% BPAR episodes and 25% of patients were lost, mainly due to infections. RTx in ESRD (≥55 years) patients has acceptable patient and graft survival if found to have cardiac fitness and therefore should be encouraged.
- Subjects
INDIA; CHRONIC kidney failure; ACADEMIC medical centers; CHI-squared test; COMPARATIVE studies; DEAD; FISHER exact test; KIDNEY transplantation; ORGAN donors; HEALTH outcome assessment; SURVIVAL; T-test (Statistics); TREATMENT effectiveness; DATA analysis software; DESCRIPTIVE statistics; KAPLAN-Meier estimator; LOG-rank test; SURGERY
- Publication
Indian Journal of Nephrology, 2014, Vol 24, Issue 1, p9
- ISSN
0971-4065
- Publication type
Article
- DOI
10.4103/0971-4065.125049