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- Title
Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway.
- Authors
Vermijlen, David; Luo, Dianzhong; Froelich, Christopher J.; Medema, Jan P.; Kummer, Jean A.; Willems, Erik; Braet, Filip; Wisse, Eddie
- Abstract
A conference paper that examines the mechanism hepatic natural killer (NK) cells use to kill P815 mystocytoma cells is presented. Results reveal that hepatic NK cells induced nucleus condensation and fragmentation in P815 cells. Chromatin was condensed into masses that abutted the inner surface of the nuclear envelope and was accompanied by nuclear fragmentation.
- Subjects
KILLER cells; LIVER cells; IMMUNOCOMPETENT cells; CELL death; FRAGMENTATION reactions
- Publication
Comparative Hepatology, 2004, Vol 3, pS58
- ISSN
1476-5926
- Publication type
Conference Paper
- DOI
10.1186/1476-5926-2-S1-S58