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- Title
Comprehensive medical treatment of women with Turner syndrome may improve pregnancy outcomes: A case report.
- Authors
Soichiro Obata; Taku Tsuburai; Ryosuke Shindo; Shigeru Aoki; Etsuko Miyagi; Hideya Sakakibara
- Abstract
A 35-year-old primiparous woman was diagnosed with Turner syndrome at the age of 12 yr due to short stature. Her karyotype showed a mosaic pattern [45, X(19)/46, XX(11)]. She had been followed up by the pediatric service. GH was not prescribed because, although she was of relatively short stature, her growth trajectory was reasonable. She was started on estrogen replacement therapy at 15 yr of age and switched to Kaufmann therapy after 1 yr. After transitioning her care to the gynecology service at 20 yr of age, she was screened for complications and Kaufmann therapy was continued. No abnormalities were detected in the pre-pregnancy screening. She conceived by in vitro fertilization and embryo transplantation with oocyte donation. No severe complications occurred during gestation, and she gave birth to a female neonate vaginally at 41 wk and 6 d of gestation. The neonate's birthweight was 3166 g, and her Apgar scores were 8 and 9 at 1 and 5 min, respectively. No severe complications occurred during the postpartum period. Comprehensive medical treatment and appropriate transition from pediatric to adult services may improve the pregnancy outcomes of women with Turner syndrome.
- Subjects
TURNER'S syndrome; THERAPEUTICS; FERTILIZATION in vitro; GONADAL dysgenesis; ESTROGEN replacement therapy; PREGNANCY
- Publication
Clinical Pediatric Endocrinology, 2019, Vol 28, Issue 2, p37
- ISSN
0918-5739
- Publication type
Article
- DOI
10.1297/cpe.28.37