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- Title
Molecular detection and characterization of SARS-CoV-2 in cats and dogs of positive owners during the first COVID-19 wave in Brazil.
- Authors
Galhardo, Juliana Arena; Barbosa, David Soeiro; Kmetiuk, Louise Bach; de Carvalho, Otávio Valério; Teixeira, Ana Izabel Passarella; Fonseca, Paula Luize Camargos; de Araújo e Santos, Luiza Campos Guerra; Queiroz, Daniel Costa; Miranda, João Victor Oliveira; da Silva Filho, Aluisio Pereira; Castillo, Anisleidy Pérez; Araujo, Ricardo Nascimento; da Silveira, Julia Angelica Gonçalves; Ristow, Luiz Eduardo; Brandespim, Daniel Friguglietti; Pettan-Brewer, Christina; de Sá Guimarães, Ana Marcia; Dutra, Valéria; de Morais, Helio Autran; dos Santos, Andrea Pires
- Abstract
Despite previous reports of SARS-CoV-2 infection in dogs and cats worldwide, the type of swab sample used for its detection through RT-qPCR needs to be better compared and described. Accordingly, as part of a multicenter study in Brazil, the aim of the present study was to assess which rectal or oropharyngeal swabs would be more appropriate for detecting SARS-CoV-2 in cats and dogs, through viral load comparison. Pets of owners diagnosed with COVID-19 in the last 7 days were eligible. A total of 148 animals from four of the five Brazilian geographical regions were analyzed, among which 10/48 cats (20.83%) and 11/100 dogs (11.00%) were positive. The results suggested that oropharyngeal swabs should be considered for SARS-CoV-2 detection, particularly in cats, due to the higher cDNA viral load. Also, the genomic results showed similarities between SARS-CoV-2 animal variants and human variants that were circulating at the time of sampling, thus corroborating the existence of zooanthroponotic transmission. In conclusion, the present study highlighted the importance of SARS-CoV-2 monitoring among cats and dogs, as virus modification may indicate the possibility of mutations in animals and spillover back to owners. Thus, positive individuals should always self-isolate from their pets during COVID-19, to prevent trans-species transmission and mutation.
- Subjects
BRAZIL; COVID-19 pandemic; DOG owners; SARS-CoV-2; PETS; CATS; ANIMAL mutation; PET owners
- Publication
Scientific Reports, 2023, Vol 13, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-023-41285-0