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- Title
Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is spread internationally by genetically distinct gonococcal populations.
- Authors
Whiley, David M.; Goire, Namraj; Lambert, Stephen B.; Nissen, Michael D.; Sloots, Theo P.; Tapsall, John W.
- Abstract
The article provides further evidence of the international spread in Neisseria gonorrhoeae exhibiting reduced susceptibility to ceftriaxone and that gonococci strains are genotypically diverse. The study uses multilocus sequence typing (MLST) to further examine the genotypic diversity of 20 gonococci exhibiting a range of ceftriaxone minimum inhibitory concentrations (MICs) and including isolates with and without penicillin-binding protein 2 (PBP2). It notes that the isolates were taken from a previous study and were selected retrospectively.
- Subjects
NEISSERIA gonorrhoeae; PENICILLIN; ANTI-infective agents; DRUG therapy; THERAPEUTICS
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2011, Vol 66, Issue 5, p1186
- ISSN
0305-7453
- Publication type
Article
- DOI
10.1093/jac/dkr052