We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Streamlined analysis of LINCS L1000 data with the slinky package for R.
- Authors
Kort, Eric J; Jovinge, Stefan
- Abstract
Summary The L1000 dataset from the NIH LINCS program holds the promise to deconvolute a wide range of biological questions in transcriptional space. However, using this large and decentralized dataset presents its own challenges. The slinky package was created to streamline the process of identifying samples of interest and their corresponding control samples, and loading their associated expression data and metadata. The package can integrate with workflows leveraging the BioConductor collection of tools by encapsulating the L1000 data as a SummarizedExperiment object. Availability and implementation Slinky is freely available as an R package at http://bioconductor.org/packages/slinky
- Subjects
PACKAGING; METADATA
- Publication
Bioinformatics, 2019, Vol 35, Issue 17, p3176
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btz002