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- Title
Cost-effectiveness of induction of labour at term with a Foley catheter compared to vaginal prostaglandin E<sub>2</sub> gel ( PROBAAT trial).
- Authors
Baaren, GJ; Jozwiak, M; Opmeer, BC; Oude Rengerink, K; Benthem, M; Dijksterhuis, MGK; Huizen, ME; Salm, PCM; Schuitemaker, NWE; Papatsonis, DNM; Perquin, DAM; Porath, M; Post, JAM; Rijnders, RJP; Scheepers, HCJ; Spaanderman, M; Pampus, MG; Leeuw, JW; Mol, BWJ; Bloemenkamp, KWM
- Abstract
Objective To assess the economic consequences of labour induction with Foley catheter compared to prostaglandin E2 gel. Design Economic evaluation alongside a randomised controlled trial. Setting Obstetric departments of one university and 11 teaching hospitals in the Netherlands. Population Women scheduled for labour induction with a singleton pregnancy in cephalic presentation at term, intact membranes and an unfavourable cervix; and without previous caesarean section. Methods Cost-effectiveness analysis from a hospital perspective. Main outcome measures We estimated direct medical costs associated with healthcare utilisation from randomisation to 6 weeks postpartum. For caesarean section rate, and maternal and neonatal morbidity we calculated the incremental cost-effectiveness ratios, which represent the costs to prevent one of these adverse outcomes. Results Mean costs per woman in the Foley catheter group ( n = 411) and in the prostaglandin E2 gel group ( n = 408), were €3297 versus €3075, respectively, with an average difference of €222 (95% confidence interval −€157 to €633). In the Foley catheter group we observed higher costs due to longer labour ward occupation and less cost related to induction material and neonatal admissions. Foley catheter induction showed a comparable caesarean section rate compared with prostaglandin induction, therefore the incremental cost-effectiveness ratio was not informative. Foley induction resulted in fewer neonatal admissions (incremental cost-effectiveness ratio €2708) and asphyxia/postpartum haemorrhage (incremental cost-effectiveness ratios €5257) compared with prostaglandin induction. Conclusions Foley catheter and prostaglandin E2 labour induction generate comparable costs.
- Subjects
COST effectiveness; URINARY catheters; PROSTAGLANDINS; INDUCED labor (Obstetrics); INDUCED ovulation; RANDOMIZED controlled trials
- Publication
BJOG: An International Journal of Obstetrics & Gynaecology, 2013, Vol 120, Issue 8, p987
- ISSN
1470-0328
- Publication type
Article
- DOI
10.1111/1471-0528.12221