We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
MODULATION OF CAPSAICIN-INDUCED NEUROGENIC VASODILATION BY ACUTE PSYCHOLOGICAL STRESS.
- Authors
SCHEAU, CRISTIAN; ILIE, MIHAELA ADRIANA; GRIGORE, OVIDIU; MIHĂILESCU, ALEXANDRA IOANA; CĂRUNTU, ANA; MIHAI, LIVIA GRAȚIELA; BĂDĂRĂU, IOANA ANCA; BODA, DANIEL; CĂRUNTU, CONSTANTIN
- Abstract
We have investigated the effect of psychological stress on capsaicin-induced cutaneous vasodilation. A total of 40 healthy volunteers were randomly included in two groups, a stress-induced group and a control group. Capsaicin was applied topically in both groups and in vivo reflectance confocal microscopy images of the dermo-epidermal junction were subsequently acquired from the same area at 0, 10, 25 and 40 minutes post-application. The capillary surface area, perimeter, and maximum diameter were evaluated comparatively between the two groups. Statistically significant higher values were obtained in the stress group at 25 and 40 minutes after exposure to capsaicin. These findings demonstrate that psychological stress can amplify the localized skin microvascular response within neurogenic inflammation induced by topical capsaicin.
- Subjects
VASODILATION; CONFOCAL microscopy; CAPSAICIN; SURFACE area; REFLECTANCE; PSYCHOLOGICAL stress
- Publication
Farmacia, 2021, Vol 69, Issue 4, p778
- ISSN
0014-8237
- Publication type
Article
- DOI
10.31925/farmacia.2021.4.20