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- Title
DESCRIPTIVE ANALYSIS OF REAL-WORLD MEDICATION PATTERNS AND ONE-YEAR OUTCOMES OF ACUTE CORONARY SYNDROME PATIENTS WITH METABOLIC SYNDROME IN A TERTIARY CARE HOSPITAL.
- Authors
PAȘC, PRISCILLA; BERDEA, DANIELA ELISABETA; DOBJANSCHI, LUCIANA; JUDEA-PUSTA, CLAUDIA TEODORA; POPESCU, MIRCEA IOACHIM
- Abstract
The prognostic association between metabolic syndrome (MS) and long-term survival of patients with acute coronary syndrome (ACS) in the era of intervention revascularization and high-precision medication had not yet been fully established. The latest ACS guidelines recommend the combined drug regimen, comprising acetylsalicylic acid (ASA), P2Y12 (purinergic receptor P2Y12) inhibitors, angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin II receptor blocker (ARB), β-blocker, and statin, to reduce recurrent ischemic cardiovascular events and mortality. The present study examined the prescription patterns of ACS long term-therapies among MS patients and analysed the association between guidelines medication and major adverse events. 49.44% of ACS patients included in this study received all five guidelinerecommended medications. Deaths occurred predominantly in MS patients receiving less medication, meanwhile major ischemic and bleeding events increased statistically with the number of drug combinations.
- Subjects
ACUTE coronary syndrome; ANGIOTENSIN-receptor blockers; METABOLIC syndrome; INTRA-abdominal hypertension; ACE inhibitors; TERTIARY care
- Publication
Farmacia, 2021, Vol 69, Issue 3, p498
- ISSN
0014-8237
- Publication type
Article
- DOI
10.31925/farmacia.2021.3.12