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- Title
Virucidal efficacy of a sonicated hydrogen peroxide system (trophon® EPR) following European and German test methods.
- Authors
Becker, Britta; Bischoff, Birte; Brill, Florian H. H.; Steinmann, Eike; Steinmann, Jochen
- Abstract
Aim: The virucidal efficacy of an automated ultrasound probe disinfector (trophon® EPR) was evaluated in a three step procedure according to Britta Becker1 Birte Bischoff1 European and German test methods. This system uses sonicated hydroFlorian H. H. Brill1 gen peroxide mist (35%) at elevated temperature (50°C) in a closed chamber with control of all parameters within a 7 minute cycle. Eike Steinmann2 Methods: In the first step of examination, the peroxide solution was tested in a quantitative suspension assay according to the Guideline Jochen Steinmann1 of Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) e.V. and Robert Koch-Institute (RKI) and in parallel with the European Norm EN 14476 with all test viruses creating a virucidal claim. 1 Dr. Brill + Partner GmbH Institute for Hygiene and Microbiology, Bremen, Germany In the second step, the virucidal efficacy of the hydrogen peroxide solution was evaluated in a hard surface carrier test according to the Guideline of DVV with adenovirus, murine norovirus and parvovirus simulating practical conditions. 2 Institute for Experimental Virology, TWINCORE Centre Finally, the efficacy was evaluated by the automated system using for Experimental and Clinical stainless steel carriers inoculated with test virus and positioned at different levels inside the chamber. Infection Research, Hannover, Germany Results: A ≥4 log10 reduction of virus titre was demonstrated with all methods including carrier tests with murine norovirus, adenovirus, and parvovirus using the automated device. Conclusion: The automated device is able to inactivate test viruses of German and European norms and can therefore claim efficacy against human pathogenic enveloped and non-enveloped viruses. This includes human papillomaviruses which form part of the complete virucidal claim.
- Publication
GMS Hygiene & Infection Control, 2017, Vol 12, p1
- ISSN
2196-5226
- Publication type
Article
- DOI
10.3205/dgkh000287