We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Risk factors of intracranial haemorrhage in preeclampsia: a case-control study.
- Authors
Keepanasseril, Anish; Subburaj, Sathiya Priya; Nayak, Deepthi; Bojja, Vandana; Chakkalakkoombil, Sunitha Vellathussery; Nair, Pradeep Pankajakshan
- Abstract
Intracranial haemorrhage (ICH) is an uncommon but one of the most devastating and potentially fatal complications of preeclampsia. Most ICHs in pregnancy are reported in the absence of a vascular lesion, and severe systolic hypertension is thought to be an important risk factor even though many reports suggest that ICH can complicate preeclampsia even at lower blood pressure levels. In this case-control study of preeclamptic women, risk factors associated with ICH were compared in women who did and did not develop ICH. During the study period, ICH occurred in 1.8% (42/2167) pregnancies with preeclampsia, with 45.2% (n = 19/42) resulting in maternal mortality. HELLP syndrome (OR = 11.5; 95% CI 3.8-34.8), multiparity (OR 3.2; 95% CI 1.4-7.7), nausea/vomiting (OR = 3.6; 95% CI 1.4-9.3), and lower educational attainment (OR = 38.2; 95% CI 3.5-423.6) were associated with the increased probability of ICH. The incidence of caesarean birth (n = 29, 74.4% vs. n = 161, 34.5%) and neonatal mortality (n = 4, 13.3% vs. n = 17, 4.0%) were higher among preeclamptic who have ICH compared to those who did not have it. Improving awareness as well as early identification of those at risk of preeclampsia and complications can limit the impact of ICH among pregnant women with preeclampsia, especially in low- to middle-income countries.
- Subjects
INTRACRANIAL hemorrhage; CASE-control method; PREECLAMPSIA; IMPACT of Event Scale; QUESTIONNAIRES; HELLP syndrome; DISEASE complications
- Publication
Neurological Sciences, 2022, Vol 43, Issue 10, p6003
- ISSN
1590-1874
- Publication type
journal article
- DOI
10.1007/s10072-022-06286-3