We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Relationships Among Markers of Inflammation, Neutrophil-to-Lymphocyte Ratio, and Syntax Severity Score in the Early Phase of Acute Coronary Syndrome.
- Authors
DUR, Ali; İSMAİLOĞLU, Ziya; İSMAİLOVA, Medine; AKBAY, Dursun; UYSAL, Ömer; METİN, Hüseyin; GÜLEN, Bedia; SÖNMEZ, Ertan
- Abstract
Objective: The aim of the present study was to examine a possible association between inflammation, as indicated by High-sensitivity C-reactive protein (HsCRP) and neutrophil/lymphocyte ratio (NLR), and the complexity and severity of coronary artery disease assessed using syntax severity score (SSS) in patients with acute coronary syndrome (ACS). Methods: Patients with symptoms suggestive of ACS who were admitted within 6 h of onset and who underwent coronary angiography were enrolled in the study. According to NLR, we divided patients into two groups: group 1 (NLR≤2.7) and group 2 (NLR>2.7). According to SSS, patients were divided into two groups: group 1 including low scores and group 2 including intermediate and high scores. Statistical analysis was performed using chi-square test and Mann–Whitney U test. Results: A total of 87 patients (65 males and 22 females) with acute myocardial infarction (AMI; 57 ST-se AMI and 30 non-ST-se AMI) were included in this study. Patients were classified into low (NLR≤2.7, n=63) and high (NLR>2.7, n=24) NLR groups. Univariate a>nalysis demonstrated that SSS was significantly higher in high NLR group than in low NLR group (23.6±12.7 versus 13.9±8.7, p<0.001). Similar to NLR, significant correlation was revealed among HsCRP, troponin levels, and SSS that indicated their predictive value in the severity of AMI. Conclusion: In present study, we showed NLR to be an independent predictor of hemodynamically significant coronary artery stenosis as measured using SSS.
- Subjects
INFLAMMATION; NEUTROPHIL lymphocyte ratio; ACUTE coronary syndrome
- Publication
Bezmialem Science, 2017, Vol 5, Issue 2, p56
- ISSN
2148-2373
- Publication type
Article
- DOI
10.14235/bs.2016.790