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- Title
The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks.
- Authors
Meng, Qing; Su, Chun-Hsien
- Abstract
This review comprehensively evaluates the effects of physical exercise on oxidative and nitrosative stress, mainly focusing on the role of antioxidants. Using a narrative synthesis approach, data from empirical studies, reviews, systematic reviews, and meta-analyses published between 2004 and 2024 were collated from databases like PubMed, EBSCO (EDS), and Google Scholar, culminating in the inclusion of 41 studies. The quality of these studies was rigorously assessed to ensure the clarity of objectives, coherence in arguments, comprehensive literature coverage, and depth of critical analysis. Findings revealed that moderate exercise enhances antioxidant defenses through hormesis, while excessive exercise may exacerbate oxidative stress. The review also highlights that while natural dietary antioxidants are beneficial, high-dose supplements could impede the positive adaptations to exercise. In conclusion, the review calls for more focused research on tailored exercise and nutrition plans to further understand these complex interactions and optimize the health outcomes for athletes and the general population.
- Subjects
OXIDATIVE stress; ATHLETES' health; SPORTS nutrition; HORMESIS; EXERCISE physiology; COOLDOWN
- Publication
Antioxidants, 2024, Vol 13, Issue 5, p573
- ISSN
2076-3921
- Publication type
Article
- DOI
10.3390/antiox13050573