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- Title
Column Plate Number and System Suitability.
- Authors
Dolan, John W.
- Abstract
The article analyses relevance of column plate number (N) for system suitability testing (SST) in liquid chromatography (LC) methods. Topics discussed include calculation of N from retention time and baseline width, use of N in evaluation of tradeoffs while changing column dimensions and LC performance, calculation of resolution using retention time of peaks and baseline width, positive relationship between N and peak height and low signal-to-noise ratios for shorter peaks.
- Subjects
LIQUID chromatography; THEORETICAL plate number; RF values (Chromatography); SIGNAL-to-noise ratio; CHROMATOGRAMS
- Publication
LC-GC Europe, 2016, Vol 29, Issue 3, p130
- ISSN
1471-6577
- Publication type
Article