Presents the case of a 32-year-old non-atopic nurse with past allergies to nickel and fragrance, and a one-year history of work-related eczema of the hands, spreading to the arms, face, neck and V of the neck. Development of co-sensitization to laureth-9 and polyquaternium-7 in a moisturizing lotion, which was repeatedly applied on pre-existing allergic contact dermatitis.