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- Title
Testing Method Performance.
- Authors
Dolan, John W.
- Abstract
The article offers advice on testing the suitability and performance of liquid chromatography (LC) systems. It provides an overview on the definitions and calculations of retention factor, resolution, tailing factor and column plate number. It suggests retaining the first peak in measuring the retention factor to prevent problems with unretained peak. It recommends the use of resolution between peak 3 and 4 for deterioration of the column or peak tailing.
- Subjects
CHEMOMETRICS; LIQUID chromatography; CHROMATOGRAPHIC analysis equipment; PARTITION coefficient (Chemistry); SEPARATION (Technology); ANALYTICAL chemistry techniques
- Publication
LC-GC Europe, 2009, Vol 22, Issue 3, p132
- ISSN
1471-6577
- Publication type
Article