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- Title
Holy smoke – high life?
- Abstract
The article deals with the artificial synthesis and derivatization of cannabinoids such as CBD and THC. It is pointed out that the term "synthetic cannabinoids" often refers to psychoactive designer drugs that can cause an (il)legal high. The biosynthesis of THCA and CBDA is explained, while THC and CBD are formed through thermal decarboxylation and have different effects. It is also mentioned that high dosage and exposure of the developing brain to THC have been associated with neurological disorders. The synthesis of THC and CBD can be achieved through the use of chiral starting materials or asymmetric catalysis. Various synthesis methods have been developed to produce these compounds, and synthetic cannabinoids have also been developed as substitutes for cannabis in the market. These can lead to severe poisoning.
- Subjects
CANNABINOID receptors; CANNABINOIDS; CANNABIS (Genus); PSYCHIATRIC drugs; CANNABIDIOL; COMPLEX compounds; SYNTHETIC marijuana; DESIGNER drugs; LIPS
- Publication
Nachrichten aus der Chemie, 2022, Vol 70, Issue 9, p76
- ISSN
1439-9598
- Publication type
Article
- DOI
10.1002/nadc.20224129508