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- Title
Chronic urticaria due to autoreactivity to progesterone.
- Authors
Wingate‐Saul, L.; Rymer, J.; Greaves, M. W.
- Abstract
A 23-year-old, regularly menstruating woman presented with recurrent urticarial eruptions, which occurred premenstrually. A skin prick test was positive for progesterone, but the urticaria was unresponsive to standard treatments. The patient was treated with goserelin (Zoladex), which suppressed her menstrual cycle, leading to the resolution of her symptoms. Subsequent flares were controlled by further goserelin injections, and the urticaria is currently in remission. However, the risks of inducing menopause artificially are significant, and alternative long-term solutions may need to be considered in the event of a relapse.
- Subjects
PROGESTERONE; PREMENSTRUAL syndrome treatment; GOSERELIN; MENSTRUAL cycle; MENOPAUSE -- Risk factors; ALTERNATIVE medicine; URTICARIA; THERAPEUTICS
- Publication
Clinical & Experimental Dermatology, 2015, Vol 40, Issue 6, p644
- ISSN
0307-6938
- Publication type
Article
- DOI
10.1111/ced.12632