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- Title
Advances of Stem Cell Therapy to Treat Heart Failure.
- Authors
Fu, Yanbin; He, Zhiying; Zhang, Chao
- Abstract
Stem cell therapy is being developed as a promising novel strategy for the treatment of heart-associated diseases. Several types of cells such as skeletal myoblasts, bone marrow (BM) mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs), adipose stem cells (ADSCs), cardiac progenitor cells (CPCs), induced pluripotent stem cells (iPSCs) have been tested in pre-clinical and clinical cardiac repairing models. Fibroblasts, as terminally differentiated cells, could also be trans-differentiated into cardiomyocytes in vitro. In this review, we will summarize the recent advances of cell types, potential applications and challenges of stem cell therapy in the treatment of heart failure.
- Subjects
STEM cell treatment; HEART failure; PROGENITOR cells; HEART cells; MYOBLASTS; PLURIPOTENT stem cells; BONE marrow examination
- Publication
Nano Life, 2019, Vol 9, Issue 3, pN.PAG
- ISSN
1793-9844
- Publication type
Article
- DOI
10.1142/S1793984419410022