We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The status of 25-hydroxyvitamin D across the spectrum of glucose tolerance among middle-aged and elderly Chinese individuals.
- Authors
Guan, Conghui; Zhen, Donghu; Tang, Xulei; Yang, Xiaomei; Zhu, Tengfei; Fu, Songbo; Tian, Yunling
- Abstract
Context Although vitamin D status and its inverse association with diabetes among White people have been recognized, little research on vitamin D status has been well conducted in Chinese individuals based on glucose tolerance. Objective To compare the vitamin D status of Chinese individuals aged 40-75 years based on the glucose tolerance status. Design and methods Serum 25 OHD was measured in a cross-sectional sample of 10 038 individuals aged 40-75 years from Lanzhou city, which is located in western China. Results People with normal glucose tolerance ( NGT, n = 4744), prediabetes ( n = 2808) or diabetes ( n = 2486) aged 40-75 years were included in the study. The difference in 25 OHD concentration between people with NGT and prediabetes was not significant (16·5 vs 16·0 ng/ml, P = 0·773), but the 25 OHD concentration of diabetes was higher than that of subjects with NGT (16·5 vs 16·5 ng/ml, P = 0·025) and prediabetes (16·5 vs 16·0 ng/ml, P = 0·032) after adjusting confounders. There was no difference in the prevalence of vitamin D deficiency between people with NGT and diabetes (74·7% vs 74·0%, P = 0·535), but the prevalence of vitamin D deficiency of prediabetes was higher than that of people with NGT (77·0% vs 74·7%, P = 0·024) and diabetes (77·0% vs 74·0%, P = 0·012). Conclusions Although vitamin D status was significantly different across the spectrum of glucose tolerance in middle-aged and elderly Chinese individuals, the difference was not clinically significant. The results, however, highlight the very high prevalence of vitamin D deficiency in this population and should raise the awareness of this important public health issue among health-care providers.
- Subjects
VITAMIN D; BLOOD sugar; DIABETES; CARBOHYDRATE intolerance; ENDOCRINE diseases
- Publication
Clinical Endocrinology, 2014, Vol 81, Issue 6, p834
- ISSN
0300-0664
- Publication type
Article
- DOI
10.1111/cen.12574