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O1‐12‐05: PHASE 1 STUDY IN HEALTHY VOLUNTEERS OF THE O‐GLCNACASE INHIBITOR ASN120290 AS A NOVEL THERAPY FOR PROGRESSIVE SUPRANUCLEAR PALSY AND RELATED TAUOPATHIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P251, doi. 10.1016/j.jalz.2018.06.2400
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- Article
Pharmacological intervention with the novel o-glcnacase inhibitor ASN-561 reduces pathological tau in transgenic mice.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P227, doi. 10.1016/j.jalz.2015.07.257
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- Article
Preclinical profiles of drug candidates promoting o-linked glycosylation of tau for the treatment of alzheimer's disease and tauopathies.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P148, doi. 10.1016/j.jalz.2014.04.110
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- Article
O1-06-01: Immunization with Aβ1-6 coupled to the virus-like particle Qβ (CAD106) efficiently removes β-amyloid without inducing Aβ-reactive T-cells
- Published in:
- 2006
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- Publication type:
- Abstract
O1-06-01: Immunization with Aβ1-6 coupled to the virus-like particle Qβ (CAD106) efficiently removes β-amyloid without inducing Aβ-reactive T-cells
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- 2006
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- Publication type:
- Abstract
Regulation of LRRK2 Expression Points to a Functional Role in Human Monocyte Maturation.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021519
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- Article
The HSP70 Molecular Chaperone Is Not Beneficial in a Mouse Model of Γ-synucleinopathy.
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- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010014
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- Article
Monocyte Chemoattractant Protein-1 Deficiency Is Protective in a Murine Stroke Model.
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- Journal of Cerebral Blood Flow & Metabolism, 2002, v. 22, n. 3, p. 308, doi. 10.1097/00004647-200203000-00008
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- Article
Increased Cerebral Infarct Volumes in Polyglobulic Mice Overexpressing Erythropoietin.
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- Journal of Cerebral Blood Flow & Metabolism, 2001, v. 21, n. 7, p. 857, doi. 10.1097/00004647-200107000-00011
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- Article
Attenuated c-fos mRNA Induction After Middle Cerebral Artery Occlusion in CREB Knockout Mice Does Not Modulate Focal Ischemic Injury.
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- Journal of Cerebral Blood Flow & Metabolism, 1998, v. 18, n. 12, p. 1325, doi. 10.1097/00004647-199812000-00007
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- Article
Neuronal Stress Response and Neuronal Cell Damage After Cardiocirculatory Arrest in Rats.
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- Journal of Cerebral Blood Flow & Metabolism, 1998, v. 18, n. 10, p. 1077, doi. 10.1097/00004647-199810000-00004
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- Publication type:
- Article
A Reproducible Model of Middle Cerebral Artery Occlusion in Mice: Hemodynamic, Biochemical, and Magnetic Resonance Imaging.
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- Journal of Cerebral Blood Flow & Metabolism, 1998, v. 18, n. 4, p. 367, doi. 10.1097/00004647-199804000-00004
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- Publication type:
- Article
Three-dimensional MRI of cerebral projections in rat brain in vivo after intracortical injection of MnCl<sub>2</sub>.
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- NMR in Biomedicine, 2003, v. 16, n. 5, p. 252, doi. 10.1002/nbm.834
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- Publication type:
- Article
Anti-Nogo-A Antibody Infusion 24 Hours After Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats.
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- Journal of Cerebral Blood Flow & Metabolism, 2003, v. 23, n. 2, p. 154, doi. 10.1097/01.WCB.0000040400.30600.AF
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- Article
Recovery and brain reorganization after stroke in adult and aged rats.
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- Annals of Neurology, 2005, v. 58, n. 6, p. 950
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- Article
Thrombolysis induces cerebral hemorrhage in a mouse model of cerebral amyloid angiopathy.
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- Annals of Neurology, 2002, v. 51, n. 6, p. 790, doi. 10.1002/ana.10210
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- Article
Novel non-carbohydrate O-GlcNAcase inhibitors with CNS drug properties as potential treatment for Alzheimer's disease and tauopathies.
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- 2013
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- Publication type:
- Abstract
Long-term protection of brain tissue from cerebral ischemia by peripherally administered peptidomimetic caspase inhibitors.
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- Drug Development Research, 2001, v. 52, n. 4, p. 579, doi. 10.1002/ddr.1161
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- Publication type:
- Article
Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond.
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- Movement Disorders, 2011, v. 26, n. 9, p. 1593, doi. 10.1002/mds.23774
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- Publication type:
- Article
The Second-Generation Active Aβ Immunotherapy CAD106 Reduces Amyloid Accumulation in APP Transgenic Mice While Minimizing Potential Side Effects.
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- Journal of Neuroscience, 2011, v. 31, n. 25, p. 9323, doi. 10.1523/JNEUROSCI.0293-11.2011
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- Publication type:
- Article