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- Title
The First Plant 5,6-Secosteroid from the Australian Arid Zone Species Frankenia foliosa.
- Authors
Tan, Yuen P.; Savchenko, Andrei I.; Broit, Natasa; Boyle, Glen M.; Parsons, Peter G.; Williams, Craig M.
- Abstract
The first B-ring 5,6-secosteroid isolated from plants was obtained from Frankenia foliosa, growing in Australia's arid zone. This rare secosteroid was shown to be active against all cell lines including head and neck squamous cell carcinoma (SCC) cancer cell lines that contain the Cdc25A phosphatase protein.
- Subjects
FRANKENIA; CANCER treatment; SQUAMOUS cell carcinoma; PHYTOTHERAPY; STEROIDS; PHARMACEUTICAL chemistry
- Publication
European Journal of Organic Chemistry, 2017, Vol 2017, Issue 11, p1498
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201700035