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- Title
Association between low fatty acid levels and platelet count in infants with Retinopathy of Prematurity.
- Authors
Lundgren, Pia; Nilsson, Anders K.; Hellgren, Gunnel; Pivodic, Aldina; Smith, Lois E.H.; Hellström, Ann
- Abstract
Thrombocytopenia was any platelet count <100 × 10 SP 9 sp /L. LC-PUFA levels and platelet counts were used to calculate weekly Pearson correlations for PMAs from 28 to 40 weeks. An ROP mouse model indicated that platelet alpha-granules released anti-angiogenic stimuli, causing downregulation of retinal VEGF-A transcripts and suppressed neovascularisation during the second ROP phase.1 Platelets are released from mature megakaryocytes in bone marrow through a series of events.
- Subjects
PLATELET count; RETROLENTAL fibroplasia; FATTY acids; INFANTS; VASCULAR endothelial growth factors; RETINAL injuries
- Publication
Acta Paediatrica, 2020, Vol 109, Issue 12, p2547
- ISSN
0803-5253
- Publication type
Article
- DOI
10.1111/apa.15406