We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Delayed Hypersensitivity, Macrophage Migration, and Antibodies in Guinea-Pigs Immunized with Diphtheria Toxoid I. Immunization with Antigen-Antibody Precipitates.
- Authors
Kostiala, Anja A. I.; Kosunen, T. U.
- Abstract
Guinea-pigs were immunized with diphtheria toxoid (DT) or with DT-antitoxin precipitate, both in Freund's complete adjuvant (FCA). DT-induced inhibition of peritoneal cell migration was equally strong in both groups and increased with time after immunization. Some guinea-pigs immunized with DT-antitoxin precipitate were boosted with DT or DT-antitoxin precipitate, both in FCA. This increased the antibody titre but did not affect 24-hour skin reactivity or migration inhibition. Migration inhibition did not correlate with anti-DT passive haemagglutinins, haemolysins, or cytophilic antibody on peritoneal cells, but did correlate with 24-hour skin reactivity.
- Subjects
GUINEA pigs; DIPHTHERIA toxin; ANTITOXINS; CELL migration; IMMUNIZATION
- Publication
Scandinavian Journal of Immunology, 1972, Vol 1, Issue 2, p143
- ISSN
0300-9475
- Publication type
Article
- DOI
10.1111/j.1365-3083.1972.tb00593.x