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- Title
Preoperative endoscopic localization of colorectal cancer and tracing lymph nodes by using carbon nanoparticles in laparoscopy.
- Authors
Qingxuan Wang; Endong Chen; Yefeng Cai; Chong Chen; Wenxu Jin; Zhouci Zheng; Yixiang Jin; Yao Chen; Xiaohua Zhang; Quan Li
- Abstract
Background: The objective of this study is to evaluate the effectiveness of preoperative endoscopic localization of colorectal cancer and tracing lymph nodes by carbon nanoparticle tattooing in laparoscopic colorectal cancer surgery. Methods: From January 2013 to December 2014, 54 patients with colorectal cancer were recruited and divided into experimental (n = 27) and control (n = 27) groups. The patients in the experimental group were localized preoperatively by endoscopic carbon nanoparticle tattooing, whereas patients in the control group were not tattooed. Results: All injection sites in the experimental group were visible to surgeons. No abdominal pain, fever, diarrhea, and other symptoms of infection were found in the experimental group. The time for detecting the tumor (2.71 ± 2.13 min versus 6.91 ± 5.16 min, p < 0.001), operation time (151.22 ± 30.66 min versus 170.26 ± 33. 13 min, p = 0.033), and blood loss during the operation (125.04 ± 29.48 mL versus 147.52 ± 34.35 mL, p = 0.013) were lower in the experimental group than in the control group. Average numbers of dissected lymph nodes in the experimental group exceeded those in the control group (14.41 ± 3.32 versus 8.96 ± 2.90, p < 0.001), and the rate of dissected lymph nodes ≥12 was higher in the experimental group than in the control group (70.37 versus 37.04%, p < 0.001). Moreover, no difference in postoperative complications was found between the two groups. Conclusions: Tattooing colorectal cancer with carbon nanoparticles in laparoscopic colorectal cancer surgery is safe and useful both in localization and lymph node tracing.
- Subjects
COLON cancer; CARBON nanotubes; LAPAROSCOPY; TATTOOING; EXPERIMENTAL groups; LYMPH nodes; ENDOSCOPY
- Publication
World Journal of Surgical Oncology, 2016, Vol 14, p1
- ISSN
1477-7819
- Publication type
Article
- DOI
10.1186/s12957-016-0987-1