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- Title
The emergence of bacterial prions.
- Authors
Giraldo, Rafael
- Abstract
This article explores the discovery and characterization of bacterial prions, specifically focusing on three examples: CbRho, ChSSB, and RepA-WH1. Bacterial prions are proteins that can adopt a misfolded, self-propagating state, similar to prions found in yeast and mammals. The article discusses the properties and functions of these bacterial prions, including their interactions with chaperone proteins and nucleic acids. It also considers the potential implications of bacterial prions for antimicrobial strategies and their similarities to amyloid diseases in humans. However, more research is needed to fully understand the structures and biology of bacterial prions.
- Subjects
SCRAPIE; PRIONS; DNA-binding proteins; RHO factor; CRYPTOCHROMES; CHIMERIC proteins; BACTERIAL proteins
- Publication
PLoS Pathogens, 2024, Vol 20, Issue 6, p1
- ISSN
1553-7366
- Publication type
Article
- DOI
10.1371/journal.ppat.1012253