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- Title
Prognostic Factors of Breast Cancer Survival in the Islamic Republic of Iran: an Additive Empirical Bayesian Approach.
- Authors
Nematolahi, Samane; Rezaianzadeh, Abbas; Zare, Najaf; Akrami, Majid; Tahmasebi, Sedighe
- Abstract
Breast cancer is a public health challenge in the Islamic Republic of Iran. Relatively few studies have dealt with large dataset and advanced statistical methods. Therefore, we aimed to investigate the role of prognostic factors on breast cancer survival using Additive Empirical Bayesian model with large data set. Breast cancer data set included 1574 women diagnosed with breast cancer from 2002 to 2012 that registered from Cancer Registry in Fars Province, Islamic Republic of Iran. Overall survival rates at 2, 3, 5 and 10 years were 0.98, 0.94, 0.87 and 0.76, respectively. Five years survival at stages 1, 2 and 3 were 0.94, 0.92 and 0.74, respectively. The younger patients with characteristics such as zero involved nodes, negative progesterone receptor, free skin and good prognostic level had a higher survival chance than others. The 5-year survival probability by stage in Fars Province was nearly the same as that reported by the American Cancer Society. The Nottingham prognostic index (NPI) related to nodal status, tumour size and nuclear grade was the main indicator of breast cancer mortality.
- Subjects
IRAN; BREAST cancer prognosis; BREAST tumors; REPORTING of diseases; LYMPH nodes; PROGESTERONE receptors; SURVIVAL analysis (Biometry); SAMPLE size (Statistics); DATA analysis software; STATISTICAL models; DESCRIPTIVE statistics; TUMOR grading
- Publication
Eastern Mediterranean Health Journal, 2017, Vol 23, Issue 11, p721
- ISSN
1020-3397
- Publication type
Article
- DOI
10.26719/2017.23.11.721