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- Title
Effect of 'Tualang Honey' on Spermatogenesis in Rats.
- Authors
M., Mahaneem; S., Siti Amrah; M. K., Yatiban; J., Hasnan
- Abstract
BACKGROUND Honey is frequently consumed by Malays for enhancement of fertility and vitality. Hence, the aim of this study was to determine the effect of Malaysian honey on spermatogenesis in rats. MATERIALS AND METHODS Male Sprague-Dawley rats, aged 8 weeks (200-230g) were treated with either 0.2, 1.2 or 2.4 g/kg/day of honey for 28 days (n=7 for each group) by gavaging. Control animals were given deionized water for the same duration. General health and body weight of the animals were monitored daily and weekly, respectively. At the end of the study, animals were sacrificed and reproductive organs were carefully removed and studied. RESULTS There were no significant differences for the percentage of body weight gain and for the absolute and relative weights of testes and male accessory organs (prostate, epididymis and seminal vesicles) among the groups. However, sperm counts were significantly higher in rats received 1.2 g/kg/day of honey (p<0.05) when compared to those in control group and in rats that received 0.2 and 2.4 g/kg/day of honey. CONCLUSION Honey could enhance spermatogenesis in rats if given at the appropriate dose. However, its mechanism of action needs to be further elucidated.
- Subjects
HONEY; SPERMATOGENESIS in animals; RATS; SPERMATOZOA; DRUG dosage
- Publication
Malaysian Journal of Medical Sciences, 2007, Vol 14, Issue 1, p126
- ISSN
1394-195X
- Publication type
Article