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- Title
Graduated elastic compression stockings in the prevention of post-thrombotic syndrome: A systematic review and meta-analysis.
- Authors
Nielsen, Jørn Dalsgaard; Hermann, Thomas Steffen; Fredskilde, Pernille Cecilie Ammundsen
- Abstract
Background: The effect of graduated elastic compression stockings (ECS) in the prevention of post-thrombotic syndrome (PTS) has been questioned since a large randomized trial found no prophylactic effect of ECS. Objective: To assess the effect of the wearing time of ECS on the incidence of post-thrombotic syndrome (PTS) after proximal deep venous thrombosis, we performed a meta-analysis of the incidence of PTS across randomized and observational studies. Method: PubMed, Embase and Cochrane databases were searched until 12 June 2023 for studies on the effect of ECS on PTS. References of eligible studies were also screened in order to identify other potential studies that might have been missed during the search. Results: Four studies comprising a total of 1467 patients met our inclusion criteria for early initiation and consistent use of ECS in patients with acute proximal DVT. ECS significantly reduced the incidence of mild-moderate PTS (OR: 0.48; 95% CI: 0.36–0.63) as well as severe PTS (OR: 0.44; 95% CI: 0.28–0.58).
- Subjects
MEDICAL information storage &; retrieval systems; COMPRESSION bandages; POSTTHROMBOTIC syndrome; VENOUS thrombosis; META-analysis; DESCRIPTIVE statistics; SYSTEMATIC reviews; MEDLINE; ODDS ratio; COMPRESSION garments; MEDICAL databases; ONLINE information services; CONFIDENCE intervals; DISEASE incidence; TIME
- Publication
Phlebology, 2024, Vol 39, Issue 4, p229
- ISSN
0268-3555
- Publication type
Article
- DOI
10.1177/02683555231225268