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- Title
Facilitative urea transporters.
- Authors
Smith, C.P.; Rousselet, G.
- Abstract
This article presents information on urea as waste product of metabolism. Urea transporter (UT) proteins are central to modulating urea movement across biological membranes, and over the past decade major steps have been made in defining their molecular identity and basic functional characteristics. The subsequent generation of reagents, including specific nucleotide probes and antisera, has led to significant advances in understanding the molecular aspects of the role played by UTs in the kidney. The number of UT-A transcripts in human has not been established. In rat, the UT-A gene gives rise, by use of alternative promoters, alternative transcriptional start sites and differential splicing.
- Subjects
URINALYSIS; NITROGEN excretion; METABOLISM; MATERIALS handling; IMMUNE serums; KIDNEYS
- Publication
Journal of Membrane Biology, 2001, Vol 183, Issue 1, p1
- ISSN
0022-2631
- Publication type
journal article
- DOI
10.1007/s00232-001-0048-7