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- Title
Contrast-Enhanced Tissue Harmonic Imaging versus Phase Inversion Harmonic Sonographic Imaging for the Delineation of Hepatocellular Carcinomas.
- Authors
Kono, Masashi; Minami, Yasunori; Iwanishi, Mina; Minami, Tomohiro; Chishina, Hirokazu; Arizumi, Tadaaki; Komeda, Yoriaki; Sakurai, Toshiharu; Takita, Masahiro; Yada, Norihisa; Ida, Hiroshi; Hagiwara, Satoru; Ueshima, Kazuomi; Nishida, Naoshi; Kudo, Masatoshi
- Abstract
Objective: To compare contrast tissue harmonic imaging (THI) with low mechanical index (MI) and conventional contrast harmonic imaging (CHI) with respect to lesion visibility of hepatocellular carcinoma (HCC). Methods: One hundred and twenty-five patients (84 men and 41 women, age range 39-94 years, mean age 74 years) with 100 naïve HCCs and 30 lesions after radiofrequency ablation (RFA) for HCC were evaluated. One hundred and four patients had liver cirrhosis of Child-Pugh class A, and the remaining 21 had Child-Pugh class B cirrhosis. The lesion conspicuity and intratumoral echogenicity during the postvascular phase were compared using conventional CHI and contrast THI with low MI. Results: The MI values ranged from 0.20 to 0.30 on convention-al CHI and from 0.30 to 0.35 on contrast THI. Regarding HCC lesion conspicuity, contrast THI with low MI was clearer in 79 lesions (60.8%), equal in 34 lesions (26.2%), and less clear in 17 lesions (13.1%) when compared with conventional CHI. The lesion conspicuity with contrast THI was significantly better than that with conventional CHI (p < 0.01). All of the postablative lesions were well delineated in patients who received RFA. Conclusion: Low-MI contrast THI was superior to conventional CHI with respect to lesion visibility of HCCs and might offer good imaging for the guiding of RFA.
- Subjects
COMPARATIVE studies; HEPATOCELLULAR carcinoma; CIRRHOSIS of the liver; COMPUTERS in medicine; PROBABILITY theory; THERAPEUTICS; ULTRASONIC imaging; CONTRAST media; ABLATION techniques; DESCRIPTIVE statistics
- Publication
Oncology, 2017, Vol 92, p29
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000451014