We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study.
- Authors
Akpolat, Nusret; Büyük, Yalçın; Uzun, İbrahim; Geçit, İlhan; Kurnaz, Gülay
- Abstract
Aim: To investigate the frequency of latent prostatic carcinoma (PCa) and prostatic intraepithelial neoplasia (PIN) in the Turkish population. Materials and methods: PCa and PIN were evaluated in 116 male autopsy cases in which the cause of death was nontumoral. All patients were Turkish, living in İstanbul, and aged 40-79 years. Results: The prevalence of PCa was 19.8% and the decade rates (decades 5-8) were 9.5%, 12.5%, 18.8%, and 37%, respectively (P < 0.011). The rates of high-grade prostatic intraepithelial neoplasia (HGPIN) were 33.3%, 31.3%, 56.3%, and 25.9% for decades 5-8, respectively (P > 0.05). A total of 68.4% of PCa cases were HGPIN. There was a statistically significant correlation among HGPIN, PCa, and Gleason scores (P < 0.002). Conclusion: The prevalence of latent PCa in the Turkish population is very high (19.7%). In order to determine latent PCa cases, males over 40 years of age must be screened more strictly.
- Subjects
PROSTATE cancer; DISEASE prevalence; AUTOPSY; EPITHELIAL tumors; MEDICAL statistics; STATISTICAL correlation; STATISTICAL significance
- Publication
Turkish Journal of Medical Sciences, 2012, Vol 42, Issue 3, p449
- ISSN
1300-0144
- Publication type
Article
- DOI
10.3906/sag-1008-1052