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- Title
Studying the Sensitivity of Graphene for Biosensor Applications.
- Authors
Usikov, A. S.; Lebedev, S. P.; Roenkov, A. D.; Barash, I. S.; Novikov, S. V.; Puzyk, M. V.; Zubov, A. V.; Makarov, Yu. N.; Lebedev, A. A.
- Abstract
We have studied the response of graphene-film-based chips on SiC substrates (the relative change in the chip resistance) to coming into contact with fluorescein (C20H12O5) in a wide range of its concentrations in a phosphate-buffered saline solution: from 1 × 10–3 to 1 × 104 ng/mL (seven orders of magnitude). Fluorescein detection seems to be a simple and cheap model experiment to study the sensory ability of graphene in the way of biochips manufacturing. It has been shown that chips with wide terraces on a surface with a step width of about 1000 nm and heights of up to 5 nm made it possible to construct the calibration dependences of chip response on fluorescein concentration.
- Subjects
GRAPHENE; SALINE solutions; FLUORESCEIN; MAGNITUDE (Mathematics); RESISTANCE to change
- Publication
Technical Physics Letters, 2020, Vol 46, Issue 5, p462
- ISSN
1063-7850
- Publication type
Article
- DOI
10.1134/S1063785020050296