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- Title
What about the Cytoskeletal and Related Proteins of Tapeworms in the Host's Immune Response? An Integrative Overview.
- Authors
Ríos-Valencia, Diana G.; Ambrosio, Javier; Tirado-Mendoza, Rocío; Carrero, Julio César; Laclette, Juan Pedro
- Abstract
Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medical importance of these parasitic diseases in humans and animal stock. Moreover, its study could offer new possibilities for the development of more effective anti-parasitic drugs, as well as better strategies for their surveillance, prevention, and control. In the present review, we compile the results of recent experiments on the cytoskeleton of these parasites and analyze how these novel findings might trigger the development of new drugs or the redesign of those currently used in addition to supporting their use as biomarkers in cutting-edge diagnostic tests.
- Subjects
CYTOSKELETAL proteins; VETERINARY parasitology; TAPEWORMS; IMMUNE response; LIVESTOCK; DRUG development
- Publication
Pathogens, 2023, Vol 12, Issue 6, p840
- ISSN
2076-0817
- Publication type
Article
- DOI
10.3390/pathogens12060840