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- Title
Noninvasive assessment of left ventricular end-diastolic pressure by deceleration time of early diastolic mitral annular velocity in patients with heart failure.
- Authors
Takemoto, Kazushi; Hirata, Kumiko; Hozumi, Takeshi; Tanimoto, Takashi; Orii, Makoto; Shiono, Yasutsugu; Matsuo, Yoshiki; Ino, Yasushi; Kitabata, Hironori; Kubo, Takashi; Tanaka, Atsushi; Akasaka, Takashi
- Abstract
Objective To examine the diagnostic ability of the deceleration time of early mitral annular velocity (e'DT) as determined by tissue Doppler velocity image, a method for assessing LV filling pressure. Backgrounds Estimation of LV filling pressure by Doppler echocardiography requires a combination of various parameters. Therefore, there remains a need for a simple index in LV filling pressure estimation. The eʹ is known to be reduced and delayed with increased LV filling pressure during development of heart failure. Thus, we hypothesized that e'DT would be shortened as LV filling pressure is increased. Methods Simultaneous LV end-diastolic pressure (LVEDP) measurement and Doppler echocardiography were performed in 94 patients who were admitted to our hospital for heart failure. Exclusion criteria were atrial fibrillation, mitral valve surgery, and acute coronary syndrome. Results The e'DT in 31 patients with LVEDP >16 mm Hg (68±13 ms) was significantly shorter than that in 63 patients with LVEDP ≤16 mm Hg (103±27 ms). Both e'DT and early transmitral flow velocity (E)/eʹ were significantly correlated with LVEDP. In 30 patients with 10-14 E/eʹ, significance of correlation in e'DT was remained, while E/eʹ was not. The area under the ROC curve for prediction of LVEDP >16 mm Hg for e′DT was greater than that for E/e′ (0.91 vs 0.74, P=.046). Conclusion The e'DT is useful to assess LV filling pressure, especially in 10-14 E/eʹ. This simple tissue Doppler index may be a potential parameter for easily distinguishing between mild and severe heart failures.
- Subjects
DIASTOLIC blood pressure; HEART failure; DOPPLER echocardiography; LEFT heart ventricle; HEART physiology; RESEARCH methodology; DIAGNOSIS
- Publication
Echocardiography, 2017, Vol 34, Issue 9, p1292
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/echo.13626