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- Title
Diagnostic yield of broncho‐alveolar lavage for pembrolizumab induced sarcoid‐like reaction of the lung.
- Authors
Grosse, Alexandra; Grosse, Claudia
- Abstract
Immune checkpoint inhibitors may cause sarcoid‐like reaction of the lung. Broncho‐alveolar lavage demonstrates lymphocytosis in this setting; the CD4+/CD8+ ratio was not increased in the current case. This pattern is similar, but not identical to sarcoidosis. Drug‐induced pneumonitis, tumour recurrence or pneumonia, the main differential diagnoses for sarcoid‐like reaction, can reliably be distinguished using broncho‐alveolar lavage.
- Subjects
IRRIGATION (Medicine); LUNGS; PNEUMONIA; DIFFERENTIAL diagnosis
- Publication
Cytopathology, 2019, Vol 30, Issue 6, p686
- ISSN
0956-5507
- Publication type
Article
- DOI
10.1111/cyt.12740