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- Title
Outcome of laser vaporization and conization for cervical intraepithelial neoplasia grade 2-3.
- Authors
Miseon Nakazawa; Yuta Tabuchi; Mizue Teramoto; Akira Nishikawa; Tsuyoshi Saito
- Abstract
Objective: Cervical intraepithelial neoplasia (CIN) is a precancerous lesion that can impair fertility through cervical conization or hysterectomy. It is known that the risk of preterm delivery is increased after cervical conization. Perinatal outcome may be improved if cervical vaporization can be used to treat CIN lesions. Methods: We use semiconductor lasers in our treatment. Laser vaporization is performed in cases where accurate tissue diagnosis is made under the colposcope and there is no intracervical lesion. We reviewed the outcomes of laser vaporization and laser conization performed at our hospital from January 2018 to January 2022 for patients with up to CIN3. Treatment results were followed and examined until January 2024. No recurrence was defined as no cytological abnormalities up to 2 years after treatment. Seventy-three patients were treated with laser conization, and 201 with vaporization. The surgical procedure was selected based on colposcopy, pathologic grade, patient age, and patient's hope for pregnancy. Results: There was no significant difference in the recurrence rate of abnormal cytology up to 2 years postoperatively between laser vaporization and laser conization for CIN2 and CIN3. There were also no significant differences in cytology abnormality and human papillomavirus (HPV) disappearance rates at 3M postoperatively. HPV type 16 was the most common, followed by 52 and 58. Conclusion: When performed according to the indications, laser vaporization for CIN2 and CIN3 provides comparable therapeutic results compared to laser conization.
- Subjects
3M Co.; CERVICAL intraepithelial neoplasia; CONIZATION; VAPORIZATION; HUMAN papillomavirus; HUMAN abnormalities; SEMICONDUCTOR lasers
- Publication
Journal of Gynecologic Oncology, 2024, Vol 35, p41
- ISSN
2005-0380
- Publication type
Article
- DOI
10.3802/jgo.2024.35.S2.P41