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- Title
Combination of cyclosporine A and methylprednisolone to treat pediatric Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome.
- Authors
Dewi, Shinta Trilaksmi; Qomariah, Laily Noor; Sarkowi, Widya Khairunisa; Puspitasari, Monika; Khalidah, Miya; Anggatama, Marcella; Rizkiani, Dwinanda Almira; Etnawati, Kristiana; Febriana, Sri Awalia
- Abstract
The treatment of epidermal necrolysis in pediatric patients remains a major challenge. Cyclosporine A has emerged as a promising therapy for epidermal necrolysis in adults; however, its efficacy in children is unclear. We present the case of a boy with Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome who was initially resistant to methylprednisolone monotherapy but improved after receiving the combination of cyclosporine A and methylprednisolone. Published reports on the use of cyclosporine A for pediatric epidermal necrolysis are also briefly reviewed.
- Subjects
TOXIC epidermal necrolysis; STEVENS-Johnson Syndrome; CYCLOSPORINE; SYNDROMES in children; METHYLPREDNISOLONE; CHILD patients
- Publication
Dermatology Reports, 2023, Vol 15, Issue 2, p87
- ISSN
2036-7406
- Publication type
Article
- DOI
10.4081/dr.2023.9656